other material
confidence high
sentiment neutral
materiality 0.60
Indaptus presents Phase 1 Decoy20 interim data: stable disease in all 4 patients
Indaptus Therapeutics, Inc.
- All four patients in first cohort showed stable disease at 4 weeks; three had progressive disease at baseline.
- Decoy20 induced transient expression of over 50 biomarkers associated with innate/adaptive anti-tumor immune responses.
- Adverse events generally tolerable, resolved within 30 minutes to 3 days; drug cleared from blood in 30-120 minutes.
- Peak cytokine/chemokine induction ~4-24 hours, returning to baseline by 24-48 hours, avoiding prolonged toxicity.