other material
confidence high
sentiment positive
materiality 0.80
BriaCell reports prelim OS up to 2x literature in ADC-refractory breast cancer subset
BriaCell Therapeutics Corp.
- 23 heavily pre-treated (median 6 prior therapies) advanced breast cancer patients, all failed ADCs (KADCYLA, ENHERTU, TRODELVY).
- Median OS up to twice that reported in comparable studies; 17 of 23 patients remain alive.
- Disease control rate of 40% in evaluable patients; PFS similar or better than last regimen in 40%.
- No toxicity-related discontinuations and no cases of Interstitial Lung Disease (ILD) with Bria-IMT regimen.