{"schema_version":"secwatch.filing_event.v1","accession":"0001493152-24-000193","form_type":"8-K","ticker":"ENVB","cik":"0000890821","company_name":"Enveric Biosciences, Inc.","filed_at":"2024-01-03T23:59:59+00:00","discovered_at":"2026-05-14T18:03:27.190376+00:00","generated_at":"2026-06-07T04:59:56.980916+00:00","sec_items":["7.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.6,"calibrated_materiality_score":0.6,"confidence":"high","headline":"Enveric corrects EB-003 binding affinity data, shows 1000x greater potency than previously reported","bullets":["EB-003 exhibits 5-HT2A partial agonism with Ki of 0.2 µM (corrected from 0.2 mM) – 1000x higher binding affinity.","EB-003 binds 5-HT1A receptor with Ki of 3.3 µM (corrected from 3.3 mM).","Enveric to initiate preclinical IND-enabling activities in early 2024 for EB-003.","EB-003 selected as lead candidate from EVM301 Series; designed to promote neuroplasticity without hallucinations.","Company used PsyAI platform to screen 51 analogs; EB-003 showed no significant head-twitch response in mice."],"urls":{"canonical":"https://secwatch.observer/filing/0001493152-24-000193","json":"https://secwatch.observer/filing/0001493152-24-000193.json","markdown":"https://secwatch.observer/filing/0001493152-24-000193.md","text":"https://secwatch.observer/filing/0001493152-24-000193.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/890821/000149315224000193/0001493152-24-000193-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/890821/000149315224000193/form8-k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-07T04:59:56.980916+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}