---
schema_version: "secwatch.filing_event.v1"
accession: "0001493152-24-006132"
form_type: "8-K"
ticker: "PALI"
cik: "0001357459"
company_name: "PALISADE BIO, INC."
filed_at: "2024-02-13T23:59:59+00:00"
generated_at: "2026-06-06T03:13:47.555677+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.6
calibrated_materiality_score: 0.6
confidence: "high"
source: SEC EDGAR
---

# Palisade Bio reduces board from 8 to 4; four directors resign, Chairman changed

## Summary
- Directors James Neal, Stephanie Diaz, Cristina Csimma, Robert Trenschel resigned immediately; no disagreement cited.
- Board cut from 8 to 4 members; Donald Williams appointed Chairman.
- Recent warrant exercise generated $2.5 million gross proceeds.
- PALI-2108 Phase 1 study on track to start before end of 2024; IND/CTA submission planned by year end.
- Positive preclinical data presented at 2024 Crohn's & Colitis Congress; second milestone payment received from IBD Ventures.

## SEC filing metadata
- accession: 0001493152-24-006132
- form_type: 8-K
- ticker: PALI
- cik: 0001357459
- company_name: PALISADE BIO, INC.
- filed_at: 2024-02-13T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.6
- calibrated_materiality_score: 0.6
- confidence: high
- sec_items: 5.02, 8.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1357459/000149315224006132/0001493152-24-006132-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1357459/000149315224006132/form8-k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001493152-24-006132
- JSON: https://secwatch.observer/filing/0001493152-24-006132.json
- Plain text: https://secwatch.observer/filing/0001493152-24-006132.txt

## Key facts
- Executive change
  Robert Trenschel resigned as Director at PALISADE BIO, INC..
  - Action: resigned
  - Role: Director
  source text: James Neal, Stephanie Diaz, Dr. Cristina Csimma, and Dr. Robert Trenschel (collectively, the “Resigning Directors”), informed the board of directors (“Board”) of Palisade Bio, Inc. (the “Company”) that each is resigning as a member of the Board effective immediately.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1357459/000149315224006132/0001493152-24-006132-index.htm
- Executive change
  James Neal resigned as Director at PALISADE BIO, INC..
  - Action: resigned
  - Role: Director
  source text: James Neal, Stephanie Diaz, Dr. Cristina Csimma, and Dr. Robert Trenschel (collectively, the “Resigning Directors”), informed the board of directors (“Board”) of Palisade Bio, Inc. (the “Company”) that each is resigning as a member of the Board effective immediately.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1357459/000149315224006132/0001493152-24-006132-index.htm
- Executive change
  Stephanie Diaz resigned as Director at PALISADE BIO, INC..
  - Action: resigned
  - Role: Director
  source text: James Neal, Stephanie Diaz, Dr. Cristina Csimma, and Dr. Robert Trenschel (collectively, the “Resigning Directors”), informed the board of directors (“Board”) of Palisade Bio, Inc. (the “Company”) that each is resigning as a member of the Board effective immediately.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1357459/000149315224006132/0001493152-24-006132-index.htm
- Executive change
  Cristina Csimma resigned as Director at PALISADE BIO, INC..
  - Action: resigned
  - Role: Director
  source text: James Neal, Stephanie Diaz, Dr. Cristina Csimma, and Dr. Robert Trenschel (collectively, the “Resigning Directors”), informed the board of directors (“Board”) of Palisade Bio, Inc. (the “Company”) that each is resigning as a member of the Board effective immediately.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1357459/000149315224006132/0001493152-24-006132-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.