---
schema_version: "secwatch.filing_event.v1"
accession: "0001493152-24-021837"
form_type: "8-K"
ticker: "LIXT"
cik: "0001335105"
company_name: "LIXTE BIOTECHNOLOGY HOLDINGS, INC."
filed_at: "2024-05-29T23:59:59+00:00"
generated_at: "2026-06-01T07:37:36.572527+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.55
calibrated_materiality_score: 0.55
confidence: "high"
source: SEC EDGAR
---

# Lixte Biotechnology notifies CMO James Miser of non-renewal; employment ends July 31, 2024

## Summary
- Dr. James Miser's employment agreement not renewed; CMO role ends July 31, 2024.
- Lixte intends to appoint a new Chief Medical Officer effective August 1, 2024.
- Notice of non-renewal provided to Dr. Miser on May 24, 2024.

## SEC filing metadata
- accession: 0001493152-24-021837
- form_type: 8-K
- ticker: LIXT
- cik: 0001335105
- company_name: LIXTE BIOTECHNOLOGY HOLDINGS, INC.
- filed_at: 2024-05-29T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.55
- calibrated_materiality_score: 0.55
- confidence: high
- sec_items: 5.02
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1335105/000149315224021837/0001493152-24-021837-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1335105/000149315224021837/form8-k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001493152-24-021837
- JSON: https://secwatch.observer/filing/0001493152-24-021837.json
- Plain text: https://secwatch.observer/filing/0001493152-24-021837.txt

## Key facts
- Executive change
  James Miser departed as Chief Medical Officer at LIXTE BIOTECHNOLOGY HOLDINGS, INC..
  - Action: elected not to renew
  - Role: Chief Medical Officer
  source text: On May 24, 2024, Lixte Biotechnology Holdings, Inc. (the “Company”) provided notice to Dr. James Miser that it has elected not to renew the employment agreement between the Company and Dr. Miser pursuant to which Dr. Miser has served as the Company’s Chief Medical Officer.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1335105/000149315224021837/0001493152-24-021837-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.