{"schema_version":"secwatch.filing_event.v1","accession":"0001493152-24-040526","form_type":"8-K","ticker":"BFRG","cik":"0001829247","company_name":"BullFrog AI Holdings, Inc.","filed_at":"2024-10-09T23:59:59+00:00","discovered_at":"2026-05-14T18:03:09.882820+00:00","generated_at":"2026-05-30T17:27:56.750527+00:00","sec_items":["7.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.65,"calibrated_materiality_score":0.65,"confidence":"high","headline":"Bullfrog AI publishes Cell Reports data supporting BF-114 for liver diseases; adds Dr. Lopa Mishra to advisory board","bullets":["Study led by Dr. Lopa Mishra published in Cell Reports provides mechanistic evidence for BF-114 target β2-spectrin (SPTBN1 siRNA) in obesity, MASLD, MASH, and HCC.","Findings show reducing β2-spectrin can halt progression of MASLD and MASH and reduce liver damage in animal models.","Dr. Lopa Mishra, a globally recognized liver disease expert, joined Bullfrog AI's Scientific Advisory Board to guide BF-114 development.","Bullfrog AI will use its bfLEAP AI platform to analyze single-cell data from animal models and human patients for further mechanistic insights.","BF-114 is an siRNA targeting SPTBN1, aimed at treating obesity-related liver diseases with high unmet need."],"urls":{"canonical":"https://secwatch.observer/filing/0001493152-24-040526","json":"https://secwatch.observer/filing/0001493152-24-040526.json","markdown":"https://secwatch.observer/filing/0001493152-24-040526.md","text":"https://secwatch.observer/filing/0001493152-24-040526.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1829247/000149315224040526/0001493152-24-040526-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1829247/000149315224040526/form8-k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-30T17:27:56.750527+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}