other material
confidence high
sentiment positive
materiality 0.65
Shuttle Pharma doses first three patients in Phase 2 trial of Ropidoxuridine for glioblastoma
Shuttle Pharmaceuticals Holdings, Inc.
- First three patients dosed in Phase 2 trial of Ropidoxuridine for glioblastoma.
- Trial targets IDH wild-type, methylation-negative glioblastoma patients with no cure.
- Initial 40 patients randomized to 1,200 mg/day or 960 mg/day; then add 14 on optimal dose.
- Expected trial completion in 18-24 months.
- Orphan Drug Designation from FDA provides potential 7-year exclusivity if approved.