{"schema_version":"secwatch.filing_event.v1","accession":"0001493152-24-046434","form_type":"8-K","ticker":"CLDI","cik":"0001855485","company_name":"Calidi Biotherapeutics, Inc.","filed_at":"2024-11-18T23:59:59+00:00","discovered_at":"2026-05-14T18:03:10.089078+00:00","generated_at":"2026-05-29T23:13:50.322974+00:00","sec_items":["7.01","9.01"],"event_type":"other_material","sentiment":"neutral","materiality_score":0.4,"calibrated_materiality_score":0.4,"confidence":"medium","headline":"Calidi presents RTNova data supporting systemic targeting of metastatic lung cancer at IOVC and SITC","bullets":["Data presented at IOVC and SITC shows RTNova enveloped virotherapy can target multiple metastatic tumor sites.","RTNova uses tumor-selective vaccinia virus engineered to produce high levels of EEVs to avoid immune clearance.","In an advanced lung metastasis model, RTNova demonstrated robust therapeutic potential as monotherapy and viral vector.","The platform can induce expression of engineered payloads in tumor cells, enabling future delivery of therapeutic genes.","Calidi plans to advance RTNova as a multi-modal systemic antitumor virotherapy and seek pharma collaborations."],"urls":{"canonical":"https://secwatch.observer/filing/0001493152-24-046434","json":"https://secwatch.observer/filing/0001493152-24-046434.json","markdown":"https://secwatch.observer/filing/0001493152-24-046434.md","text":"https://secwatch.observer/filing/0001493152-24-046434.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1855485/000149315224046434/0001493152-24-046434-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1855485/000149315224046434/form8-k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-29T23:13:50.322974+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}