{"schema_version":"secwatch.filing_event.v1","accession":"0001493152-24-049377","form_type":"8-K","ticker":"MIRA","cik":"0001904286","company_name":"MIRA PHARMACEUTICALS, INC.","filed_at":"2024-12-10T23:59:59+00:00","discovered_at":"2026-05-14T18:03:10.319133+00:00","generated_at":"2026-05-29T05:18:47.333393+00:00","sec_items":["8.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.7,"calibrated_materiality_score":0.7,"confidence":"high","headline":"Mira Pharma completes Ketamir-2 GLP safety program; no adverse findings, IND submission by year-end 2024","bullets":["Successful completion of GLP preclinical safety program for Ketamir-2; no adverse findings across cardiovascular, CNS, respiratory, and toxicology studies.","Key results: cardiovascular safety in dogs, CNS assessment in rats (transient high-dose effects), 14-day dog tox up to 200 mg/kg, Ames test non-mutagenic.","Plan to submit IND by end of 2024; Phase I trial start Q1 2025 for safety, tolerability, PK/PD, and pain evaluation.","Early Phase I data expected Q2 2025; focus on neuropathic pain and psychosis."],"urls":{"canonical":"https://secwatch.observer/filing/0001493152-24-049377","json":"https://secwatch.observer/filing/0001493152-24-049377.json","markdown":"https://secwatch.observer/filing/0001493152-24-049377.md","text":"https://secwatch.observer/filing/0001493152-24-049377.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1904286/000149315224049377/0001493152-24-049377-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1904286/000149315224049377/form8-k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-29T05:18:47.333393+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}