secwatch / observer

8-K filed January 28, 2025, 6:59 PM ET ticker SHPH CIK 0001757499

other material confidence high sentiment neutral materiality 0.55

Shuttle Pharma expands Phase 2 glioblastoma trial; adds sites, extends timeline through Jan 2026

Shuttle Pharmaceuticals Holdings, Inc.

Change Order with Theradex increases Phase 2 patients from 15 to 16 and sites from 4 to 6.
Total budget limited to $5,308,294; covers activities through 31 January 2026.
Protocol amendments versions 2.0 and 3.0 added; safety teleconferences expanded for medical monitor review.
Two sites (UNC and Georgetown) activated earlier than anticipated, driving budget increase.

item 1.01 item 9.01

Machine-readable event card

schema_version: secwatch.filing_event.v1
accession: 0001493152-25-003985
form_type: 8-K
ticker: SHPH
cik: 0001757499
company_name: Shuttle Pharmaceuticals Holdings, Inc.
filed_at: 2025-01-28T23:59:59+00:00
discovered_at: 2026-05-14T18:03:04.741458+00:00
generated_at: 2026-05-27T08:25:16.618024+00:00
sec_items: ["1.01", "9.01"]
event_type: other_material
sentiment: neutral
materiality_score: 0.55
calibrated_materiality_score: 0.55
confidence: high
secwatch_canonical_url: https://secwatch.observer/filing/0001493152-25-003985
json_url: https://secwatch.observer/filing/0001493152-25-003985.json
markdown_url: https://secwatch.observer/filing/0001493152-25-003985.md
text_url: https://secwatch.observer/filing/0001493152-25-003985.txt
edgar_index_url: https://www.sec.gov/Archives/edgar/data/1757499/000149315225003985/0001493152-25-003985-index.htm
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generated_by_model: deepseek-v4-flash:cloud@v2
review_status: machine_generated
human_reviewed: false
corrected: false
correction_note: null
correction_timestamp: null
superseded_by: null

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Source: SEC EDGAR

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