other material
confidence medium
sentiment positive
materiality 0.55
Kairos Pharma presents preclinical data for KROS 101 and KROS 401 at AACR IO
Kairos Pharma, LTD.
- KROS 101 (GITR agonist) inhibited tumor growth in melanoma model and increased CD4+/CD8+ T cell proliferation.
- KROS 101 prevented T cell exhaustion, a key advantage over prior GITR antibody TRX518.
- KROS 401 peptide inhibitor reduced M2 macrophages and showed anti-tumor effect in glioma-bearing mice.
- Data presented at AACR Immuno-Oncology conference in Los Angeles, February 23-26, 2025.
- CEO highlighted potential of KROS platform to address T cell exhaustion and reprogram tumor microenvironment.