{"schema_version":"secwatch.filing_event.v1","accession":"0001493152-25-009731","form_type":"8-K","ticker":"CLDI","cik":"0001855485","company_name":"Calidi Biotherapeutics, Inc.","filed_at":"2025-03-10T23:59:59+00:00","discovered_at":"2026-05-14T18:03:05.335115+00:00","generated_at":"2026-05-25T02:08:53.252983+00:00","sec_items":["7.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.65,"calibrated_materiality_score":0.65,"confidence":"high","headline":"Calidi Biotherapeutics reports preclinical data: systemic RTNova platform delivers gene therapy payload to tumors","bullets":["RTNova platform demonstrated killing of over 60 different tumor cell lines in preclinical models.","Single dose of 3KO RT with immunotherapeutic payload increased leukocyte infiltration to 92% vs 46% untreated.","Complete eradication of certain tumors observed in preclinical model after treatment with 3KO RT plus payload.","Platform also acts as a viral vector to express therapeutic genes at tumor sites; potential partnerships noted."],"urls":{"canonical":"https://secwatch.observer/filing/0001493152-25-009731","json":"https://secwatch.observer/filing/0001493152-25-009731.json","markdown":"https://secwatch.observer/filing/0001493152-25-009731.md","text":"https://secwatch.observer/filing/0001493152-25-009731.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1855485/000149315225009731/0001493152-25-009731-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1855485/000149315225009731/form8-k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-25T02:08:53.252983+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}