{"schema_version":"secwatch.filing_event.v1","accession":"0001493152-25-013970","form_type":"8-K","ticker":"TELO","cik":"0001971532","company_name":"Telomir Pharmaceuticals, Inc.","filed_at":"2025-09-18T23:59:59+00:00","discovered_at":"2026-05-14T18:02:45.727077+00:00","generated_at":"2026-05-17T06:17:38.468053+00:00","sec_items":["8.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.5,"calibrated_materiality_score":0.5,"confidence":"medium","headline":"Telomir-1 inhibits KDM5 demethylase families in vitro, expanding epigenetic targeting","bullets":["Telomir-1 inhibits KDM5A, KDM5B, and KDM5C in vitro, blocking silencing of tumor suppressor genes.","Adds to prior activity on KDM2/KDM6 families and DNA methylation, unique among epigenetic therapies.","Telomir-1 spared GCN5L2 acetyltransferase, indicating potential for reduced systemic toxicity.","IND-enabling studies and GMP scale-up ongoing; additional preclinical evaluations in cancer and aging."],"urls":{"canonical":"https://secwatch.observer/filing/0001493152-25-013970","json":"https://secwatch.observer/filing/0001493152-25-013970.json","markdown":"https://secwatch.observer/filing/0001493152-25-013970.md","text":"https://secwatch.observer/filing/0001493152-25-013970.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1971532/000149315225013970/0001493152-25-013970-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1971532/000149315225013970/form8-k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-17T06:17:38.468053+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}