secwatch.observer — SEC 8-K summary ====================================== Issuer: Telomir Pharmaceuticals, Inc. (TELO) CIK: 0001971532 Form: 8-K Filed at: 2025-10-14T23:59:59+00:00 Accession: 0001493152-25-017916 Event type: other_material Sentiment: positive Materiality: 0.60 Item codes: 8.01 LLM model: deepseek-v4-flash:cloud@v2 Telomir Pharma reports Telomir-1 kills pancreatic cancer cells in vitro; plans further studies -------------------------------------------------------------------------------- - Telomir-1 reduced survival of aggressive human pancreatic cancer (PANC-1) cells in concentration-dependent manner. - Effects partially reversed by iron re-addition, suggesting iron-dependent processes contribute to response. - Telomir-1 previously shown to influence tumor suppressor genes and iron-dependent histone demethylases relevant to pancreatic cancer. - Pancreatic cancer has five-year survival rate of ~12%; current treatments limited by toxicity and resistance. - Telomir plans to expand preclinical research to leukemia models and initiate in vivo validation studies for IND preparation. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1971532/000149315225017916/0001493152-25-017916-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1971532/000149315225017916/form8-k.htm HTML page: https://secwatch.observer/filing/0001493152-25-017916 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer