{"schema_version":"secwatch.filing_event.v1","accession":"0001493152-25-021418","form_type":"8-K","ticker":"CLDI","cik":"0001855485","company_name":"Calidi Biotherapeutics, Inc.","filed_at":"2025-11-10T23:59:59+00:00","discovered_at":"2026-05-14T18:02:40.835002+00:00","generated_at":"2026-05-16T22:37:26.565393+00:00","sec_items":["7.01","8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.7,"calibrated_materiality_score":0.7,"confidence":"high","headline":"Calidi presents positive preclinical data on CLD-401 at SITC; IND filing expected by end 2026","bullets":["CLD-401 protected from immune clearance and replicates specifically in tumor cells after systemic administration.","Systemic CLD-401 achieves tumor IL-15 superagonist levels comparable to localized Anktiva dosing, with minimal systemic exposure.","IND-enabling studies ongoing; IND submission expected by end of 2026.","Company actively seeking strategic partnerships to accelerate clinical development.","Investor day held at SITC featuring experts Dr. Zamarin (Mount Sinai) and Dr. Wrangle (MUSC)."],"urls":{"canonical":"https://secwatch.observer/filing/0001493152-25-021418","json":"https://secwatch.observer/filing/0001493152-25-021418.json","markdown":"https://secwatch.observer/filing/0001493152-25-021418.md","text":"https://secwatch.observer/filing/0001493152-25-021418.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1855485/000149315225021418/0001493152-25-021418-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1855485/000149315225021418/form8-k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-16T22:37:26.565393+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}