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MIRA Pharmaceuticals Publishes Peer-Reviewed Manuscript on SKNY-1 Preclinical Data
MIRA PHARMACEUTICALS, INC.
- Manuscript titled 'SKNY-1, a THCV Analog, Produces Weight Loss, Lipid Normalization and Attenuation of Reward-Associated Behaviors' published in International Journal of Molecular Sciences.
- SKNY-1 oral administration produced approximately 30% reduction in body weight from baseline after six days in the higher-dose group.
- SKNY-1 demonstrated differential CB1 signaling, partial CB2 agonist activity, and selective MAO-B inhibition relative to MAO-A.
- Preclinical findings included normalization of total cholesterol and LDL, increased HDL, reduced hepatic triglycerides, and attenuated compulsive feeding and nicotine-seeking behaviors.
- SKNY-1 has not been approved by the FDA; safety and efficacy not yet established in humans.
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