{"schema_version":"secwatch.filing_event.v1","accession":"0001493152-26-022608","form_type":"8-K","ticker":"MIRA","cik":"0001904286","company_name":"MIRA PHARMACEUTICALS, INC.","filed_at":"2026-05-13T11:30:40+00:00","discovered_at":"2026-05-13T11:35:00.272589+00:00","generated_at":"2026-05-13T11:39:25.398560+00:00","sec_items":["8.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.55,"calibrated_materiality_score":0.55,"confidence":"high","headline":"MIRA Pharmaceuticals Publishes Peer-Reviewed Manuscript on SKNY-1 Preclinical Data","bullets":["Manuscript titled 'SKNY-1, a THCV Analog, Produces Weight Loss, Lipid Normalization and Attenuation of Reward-Associated Behaviors' published in International Journal of Molecular Sciences.","SKNY-1 oral administration produced approximately 30% reduction in body weight from baseline after six days in the higher-dose group.","SKNY-1 demonstrated differential CB1 signaling, partial CB2 agonist activity, and selective MAO-B inhibition relative to MAO-A.","Preclinical findings included normalization of total cholesterol and LDL, increased HDL, reduced hepatic triglycerides, and attenuated compulsive feeding and nicotine-seeking behaviors.","SKNY-1 has not been approved by the FDA; safety and efficacy not yet established in humans."],"urls":{"canonical":"https://secwatch.observer/filing/0001493152-26-022608","json":"https://secwatch.observer/filing/0001493152-26-022608.json","markdown":"https://secwatch.observer/filing/0001493152-26-022608.md","text":"https://secwatch.observer/filing/0001493152-26-022608.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1904286/000149315226022608/0001493152-26-022608-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1904286/000149315226022608/form8-k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud","generated_at":"2026-05-13T11:39:25.398560+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}