{"schema_version":"secwatch.filing_event.v1","accession":"0001493152-26-032091","form_type":"8-K","ticker":"MIRA","cik":"0001904286","company_name":"MIRA PHARMACEUTICALS, INC.","filed_at":"2026-07-06T13:00:15+00:00","discovered_at":"2026-07-06T13:01:00.257474+00:00","generated_at":"2026-07-06T13:01:14.883592+00:00","sec_items":["7.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.65,"calibrated_materiality_score":0.65,"confidence":"high","headline":"MIRA's SKNY-1 shows favorable oral bioavailability, brain penetration in preclinical studies","bullets":["Optimized oral formulation of SKNY-1 demonstrated favorable oral bioavailability and reproducible systemic exposure in preclinical PK study.","Robust brain penetration and substantial liver exposure observed; peak plasma concentrations at 6-12 hours support once-daily oral dosing.","Findings complement prior efficacy studies showing weight reduction, lean mass preservation, and reduced compulsive feeding/nicotine-seeking.","SKNY-1 designed with biased CB1 modulation, CB2 agonism, and selective MAO-B inhibition; no anxiety-like behavior in preclinical model."],"urls":{"canonical":"https://secwatch.observer/filing/0001493152-26-032091","json":"https://secwatch.observer/filing/0001493152-26-032091.json","markdown":"https://secwatch.observer/filing/0001493152-26-032091.md","text":"https://secwatch.observer/filing/0001493152-26-032091.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1904286/000149315226032091/0001493152-26-032091-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1904286/000149315226032091/form8-k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-07-06T13:01:14.883592+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}