---
schema_version: "secwatch.filing_event.v1"
accession: "0001493152-26-036742"
form_type: "8-K"
ticker: "TELO"
cik: "0001971532"
company_name: "Telomir Pharmaceuticals, Inc."
filed_at: "2026-08-10T12:00:30+00:00"
generated_at: "2026-08-10T12:05:47.436466+00:00"
event_type: "other_material"
sentiment: "positive"
materiality_score: 0.55
calibrated_materiality_score: 0.55
confidence: "high"
source: SEC EDGAR
---

# Telomir publishes peer-reviewed preclinical data showing Telomir-Zn suppresses tumor growth in TNBC and prostate models

## Summary
- Telomir-Zn inhibits KDM histone demethylases by depleting intracellular iron; iron-rescue experiments confirmed mechanism specificity in TNBC cells.
- In HCC1806 TNBC xenografts, Telomir-Zn significantly reduced metastatic dissemination; combined with paclitaxel in BT-549 models showed synergistic tumor reduction.
- In prostate cancer model, oral Telomir-Zn reactivated silenced tumor-suppressor genes STAT1, GSTP1, RASSF1A, CDKN2A, and MASPIN.
- Selective killing: TNBC cancer cells killed at low concentrations while normal cells unharmed at >50-fold higher concentrations; MDA-MB-231 xenografts did not respond.
- Data supports planned Phase 1/2 TNBC trial under active FDA IND; CEO Erez Aminov cites limited options for advanced TNBC patients.

## SEC filing metadata
- accession: 0001493152-26-036742
- form_type: 8-K
- ticker: TELO
- cik: 0001971532
- company_name: Telomir Pharmaceuticals, Inc.
- filed_at: 2026-08-10T12:00:30+00:00
- event_type: other_material
- sentiment: positive
- materiality_score: 0.55
- calibrated_materiality_score: 0.55
- confidence: high
- sec_items: 7.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1971532/000149315226036742/0001493152-26-036742-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1971532/000149315226036742/form8-k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001493152-26-036742
- JSON: https://secwatch.observer/filing/0001493152-26-036742.json
- Plain text: https://secwatch.observer/filing/0001493152-26-036742.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.