---
schema_version: "secwatch.filing_event.v1"
accession: "0001493152-26-041011"
form_type: "8-K"
ticker: "SHPH"
cik: "0001757499"
company_name: "Shuttle Pharmaceuticals Holdings, Inc."
filed_at: "2026-09-01T20:05:38+00:00"
generated_at: "2026-09-01T20:07:11.647471+00:00"
event_type: "other_material"
sentiment: "neutral"
materiality_score: 0.5
calibrated_materiality_score: 0.5
confidence: "high"
source: SEC EDGAR
---

# Shuttle Pharma amends merger milestone: Mining Rigs threshold cut from 2,000 to 500

## Summary
- First Amendment to Merger Agreement with United Dogecoin reduces Milestone Event Mining Rigs requirement from 2,000 to 500.
- Company seeks parallel amendments to April 30, 2026 Securities Purchase Agreement and Second Amendment to Asset Purchase Agreement.
- No other terms of Merger Agreement changed; max pre-funded warrants issuable unchanged.
- Amendment effective August 31, 2026; signed by Co-CEO Chris Cooper and United Dogecoin CEO Ryan Trasolini.

## SEC filing metadata
- accession: 0001493152-26-041011
- form_type: 8-K
- ticker: SHPH
- cik: 0001757499
- company_name: Shuttle Pharmaceuticals Holdings, Inc.
- filed_at: 2026-09-01T20:05:38+00:00
- event_type: other_material
- sentiment: neutral
- materiality_score: 0.5
- calibrated_materiality_score: 0.5
- confidence: high
- sec_items: 1.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1757499/000149315226041011/0001493152-26-041011-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1757499/000149315226041011/form8-k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001493152-26-041011
- JSON: https://secwatch.observer/filing/0001493152-26-041011.json
- Plain text: https://secwatch.observer/filing/0001493152-26-041011.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.