---
schema_version: "secwatch.filing_event.v1"
accession: "0001493152-26-043053"
form_type: "8-K"
ticker: "TELO"
cik: "0001971532"
company_name: "Telomir Pharmaceuticals, Inc."
filed_at: "2026-09-17T12:30:40+00:00"
generated_at: "2026-09-17T12:35:10.207346+00:00"
event_type: "other_material"
sentiment: "positive"
materiality_score: 0.6
calibrated_materiality_score: 0.6
confidence: "high"
source: SEC EDGAR
---

# Telomir reports peer-reviewed study: Telomir-Zn restores retinal structure/function in AMD model

## Summary
- Telomir-Zn restored visual function and retinal structure after 14 days oral treatment in zebrafish AMD model; published in Int. J. Mol. Sci. 2026, 27(18), 8265.
- Treatment reduced mitochondrial oxidative stress and restored thickness across multiple retinal layers including outer/inner nuclear, outer plexiform, and ganglion cell layers.
- Telomir-Zn inhibited Fe²⁺-dependent Jumonji C histone demethylases across KDM2/KDM5/KDM6 families, strongest against KDM5B (IC50 63 nM).
- Dose-dependent increase in relative telomeric DNA content toward wild-type profile and restoration of DNA methylation at aging-associated CpG loci.
- Clinical priority remains oncology: FDA-cleared Phase 1/2 trial of Telomir-Zn in advanced or metastatic triple-negative breast cancer.

## SEC filing metadata
- accession: 0001493152-26-043053
- form_type: 8-K
- ticker: TELO
- cik: 0001971532
- company_name: Telomir Pharmaceuticals, Inc.
- filed_at: 2026-09-17T12:30:40+00:00
- event_type: other_material
- sentiment: positive
- materiality_score: 0.6
- calibrated_materiality_score: 0.6
- confidence: high
- sec_items: 7.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1971532/000149315226043053/0001493152-26-043053-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1971532/000149315226043053/form8-k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001493152-26-043053
- JSON: https://secwatch.observer/filing/0001493152-26-043053.json
- Plain text: https://secwatch.observer/filing/0001493152-26-043053.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.