secwatch.observer — SEC 8-K summary ====================================== Issuer: Karyopharm Therapeutics Inc. (KPTI) CIK: 0001503802 Form: 8-K Filed at: 2025-09-11T23:59:59+00:00 Accession: 0001503802-25-000006 Event type: leadership Sentiment: neutral Materiality: 0.35 Item codes: 5.02 LLM model: deepseek-v4-flash:cloud@v2 Karyopharm Therapeutics director Mansoor Raza Mirza resigns from board effective Sept 8, 2025 -------------------------------------------------------------------------------- - Mansoor Raza Mirza, M.D. resigned from the Board of Directors due to competing professional demands. - Resignation effective September 8, 2025; not due to any disagreement with the Company. - Consulting agreement with Mirza Consulting terminated effective September 8, 2025. - Dr. Mirza also resigning as Chief Oncologist at Copenhagen University National Medical Center effective Oct 1, 2025. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1503802/000150380225000006/0001503802-25-000006-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1503802/000150380225000006/kpti-20250905.htm HTML page: https://secwatch.observer/filing/0001503802-25-000006 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer