Akebia amends Medice license to supply vadadustat and grant manufacturing rights

Akebia Therapeutics, Inc.

Amendment #1 to License Agreement signed Nov 12, 2025 with MEDICE Arzneimittel Putter GmbH & Co. KG.
Akebia agrees to supply vadadustat drug substance under a concurrent supply agreement.
Medice granted right to manufacture Vafseo tablets using supplied drug substance.
Any know-how or patent rights from Medice's manufacturing owned by Akebia.

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