other material
confidence high
sentiment positive
materiality 0.85
Nurix Therapeutics outlines 2024 priorities: BTK degrader NX-5948 acceleration, partial hold on NX-2127
Nurix Therapeutics, Inc.
- Positive Phase 1 data for NX-5948 (BTK degrader) in CLL/NHL; plans to accelerate enrollment toward pivotal trials.
- NX-2127 Phase 1 partial clinical hold; Nurix expects to resolve with new drug product in ongoing trial.
- Gilead licensed oral IRAK4 degrader NX-0479 for $20M fee; up to $425M milestones plus tiered royalties.
- Pfizer (Seagen) collaboration for Degrader-Antibody Conjugates; $60M upfront, up to $3.4B milestones.
- Cash of $329M (Aug 2023) plus $60M from Pfizer; runway into H2 2025.