{"schema_version":"secwatch.filing_event.v1","accession":"0001558370-21-011209","form_type":"8-K","ticker":"OKUR","cik":"0001637715","company_name":"OnKure Therapeutics, Inc.","filed_at":"2021-08-11T23:59:59+00:00","discovered_at":"2026-05-14T18:04:18.963916+00:00","generated_at":"2026-06-29T15:11:28.919264+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.55,"calibrated_materiality_score":0.55,"confidence":"high","headline":"Reneo Pharma Q2 net loss $9.2M vs $3.7M; cash $167.3M; STRIDE study first patient dosed","bullets":["Net loss of $9.2M ($0.43/share) for Q2 2021, compared to net loss of $3.7M ($1.82/share) in Q2 2020.","Cash, cash equivalents and short-term investments of $167.3M as of June 30, 2021.","First patient dosed in Phase 2b STRIDE trial of REN001 in primary mitochondrial myopathies (PMM); McArdle disease study enrollment completed.","R&D expenses increased to $6.3M from $2.8M; G&A expenses rose to $2.9M from $0.9M.","Anticipated milestones: McArdle results Q1 2022, LC-FAOD results H1 2022, FORWARD study results H2 2022."],"urls":{"canonical":"https://secwatch.observer/filing/0001558370-21-011209","json":"https://secwatch.observer/filing/0001558370-21-011209.json","markdown":"https://secwatch.observer/filing/0001558370-21-011209.md","text":"https://secwatch.observer/filing/0001558370-21-011209.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1637715/000155837021011209/0001558370-21-011209-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1637715/000155837021011209/rphm-20210811x8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-29T15:11:28.919264+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}