---
schema_version: "secwatch.filing_event.v1"
accession: "0001558370-21-013985"
form_type: "8-K"
ticker: "ACRS"
cik: "0001557746"
company_name: "Aclaris Therapeutics, Inc."
filed_at: "2021-11-02T23:59:59+00:00"
generated_at: "2026-06-28T15:07:34.399132+00:00"
event_type: "earnings"
sentiment: "negative"
materiality_score: 0.65
calibrated_materiality_score: 0.65
confidence: "high"
source: SEC EDGAR
---

# Aclaris Q3 net loss widens to $21.1M; cash $243.6M; IND filed for ATI-2138

## Summary
- Net loss Q3 2021: $21.1M vs $10.7M in Q3 2020; revenue $1.7M vs $1.4M.
- Cash, cash equivalents and marketable securities of $243.6M as of Sep 30, 2021; runway through end of 2024.
- IND submitted in Oct 2021 for ATI-2138, an oral ITK/TXK/JAK3 inhibitor for psoriasis.
- Zunsemetinib (ATI-450) Phase 2b in RA planned Q4 2021; Phase 2 trials in psoriatic arthritis and hidradenitis suppurativa planned.
- Kamil Ali-Jackson, Chief Legal Officer and Co-Founder, retiring effective Jan 3, 2022; severance includes salary, bonus, vesting acceleration.

## SEC filing metadata
- accession: 0001558370-21-013985
- form_type: 8-K
- ticker: ACRS
- cik: 0001557746
- company_name: Aclaris Therapeutics, Inc.
- filed_at: 2021-11-02T23:59:59+00:00
- event_type: earnings
- sentiment: negative
- materiality_score: 0.65
- calibrated_materiality_score: 0.65
- confidence: high
- sec_items: 2.02, 5.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1557746/000155837021013985/0001558370-21-013985-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1557746/000155837021013985/acrs-20211101x8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001558370-21-013985
- JSON: https://secwatch.observer/filing/0001558370-21-013985.json
- Plain text: https://secwatch.observer/filing/0001558370-21-013985.txt

## Key facts
- Executive change
  Kamil Ali-Jackson retired as Chief Legal Officer, Chief Compliance Officer, and Corporate Secretary at Aclaris Therapeutics, Inc..
  - Action: retired
  - Role: Chief Legal Officer, Chief Compliance Officer, and Corporate Secretary
  source text: On November 1, 2021, Ms. Ali-Jackson notified the Company that she will retire from her position as the Chief Legal Officer, Chief Compliance Officer and Corporate Secretary of the Company, effective January 3, 2022
  evidence_url: https://www.sec.gov/Archives/edgar/data/1557746/000155837021013985/0001558370-21-013985-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.