secwatch.observer — SEC 8-K summary ====================================== Issuer: Voyager Therapeutics, Inc. (VYGR) CIK: 0001640266 Form: 8-K Filed at: 2022-05-04T23:59:59+00:00 Accession: 0001558370-22-007048 Event type: earnings Sentiment: positive Materiality: 0.75 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Voyager Q1 net loss $21.3M, inked Novartis deal for $54M upfront ---------------------------------------------------------------- - Q1 net loss $21.3M; collaboration revenue $0.7M (down from $6.5M YoY); cash $166.8M, runway into 2024. - Novartis license option: $54M upfront, up to $1.5B milestones for TRACER capsids on up to 5 CNS targets. - Alfred Sandrock appointed CEO (March 2022); Robin Swartz promoted to COO. - TRACER AAV9 capsid yields 50-60x better brain transduction in mice/macaques vs AAV9; AAV5 capsid 20x vs AAV9. - Preclinical data: vectorized HER2 antibody reduces tumor burden; GBA1, SOD1, anti-tau programs advancing. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1640266/000155837022007048/0001558370-22-007048-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1640266/000155837022007048/vygr-20220504x8k.htm HTML page: https://secwatch.observer/filing/0001558370-22-007048 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer