{"schema_version":"secwatch.filing_event.v1","accession":"0001558370-22-008448","form_type":"8-K","ticker":"MGTX","cik":"0001735438","company_name":"MeiraGTx Holdings plc","filed_at":"2022-05-12T23:59:59+00:00","discovered_at":"2026-05-14T18:04:02.059834+00:00","generated_at":"2026-06-25T18:51:56.501883+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.65,"calibrated_materiality_score":0.65,"confidence":"high","headline":"MeiraGTx Q1 net loss widens to $0.70 per share; Phase 3 XLRP trial actively dosing","bullets":["Net loss of $31.0M ($0.70 per share) vs $23.6M ($0.54) in Q1 2021; R&D spend rose to $23.1M.","Cash and equivalents of $114M plus $13.1M Janssen receivable; runway into Q4 2023.","Phase 3 Lumeos trial of botaretigene sparoparvovec for XLRP actively dosing patients; BLA submission targeted in 2024.","Phase 1 AQUAx trial for radiation-induced xerostomia completed all cohorts; Phase 2 planned by year-end 2022.","IND for AAV-GAD in Parkinson's filed May 2022; riboswitch platform advancing to first-in-human studies by end of 2022."],"urls":{"canonical":"https://secwatch.observer/filing/0001558370-22-008448","json":"https://secwatch.observer/filing/0001558370-22-008448.json","markdown":"https://secwatch.observer/filing/0001558370-22-008448.md","text":"https://secwatch.observer/filing/0001558370-22-008448.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1735438/000155837022008448/0001558370-22-008448-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1735438/000155837022008448/mgtx-20220512x8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-25T18:51:56.501883+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}