secwatch.observer — SEC 8-K summary ====================================== Issuer: CRESCENT BIOPHARMA, INC. (CBIO) CIK: 0001253689 Form: 8-K Filed at: 2022-08-03T23:59:59+00:00 Accession: 0001558370-22-011768 Event type: earnings Sentiment: neutral Materiality: 0.60 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 GlycoMimetics Q2 cash $60.2M; FDA clears GMI-1687 IND; uproleselan Phase 3 data expected mid-2023 -------------------------------------------------------------------------------- - Cash and cash equivalents $60.2M as of June 30, 2022, down from $90.3M at Dec 31, 2021. - R&D expenses $8.0M (down from $10.2M YoY) due to lower uproleselan trial costs after enrollment ended. - G&A expenses $5.5M (up from $4.2M) for commercial start-up costs for uproleselan. - FDA cleared IND for GMI-1687 in sickle cell disease; company seeks licensing partner. - Phase 3 uproleselan trial (n=388) on track; survival events trigger expected mid-2023 with top-line data soon after. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1253689/000155837022011768/0001558370-22-011768-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1253689/000155837022011768/glyc-20220803x8k.htm HTML page: https://secwatch.observer/filing/0001558370-22-011768 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer