earnings
confidence high
sentiment positive
materiality 0.70
Olema Pharma Q3 net loss $22.7M; cash $222.6M; OP-1250 shows 41% tumor reduction
Olema Pharmaceuticals, Inc.
2022-Q3 EPS reported
-$1.97
- Net loss $22.7M in Q3 2022 vs $17.7M in Q3 2021; R&D expenses $17.6M GAAP ($14.8M non-GAAP).
- Cash, equivalents and marketable securities $222.6M at Sept 30, 2022; sufficient into H2 2024.
- OP-1250 monotherapy: 41% of heavily pre-treated patients had tumor reduction; 6 partial responses; Phase 2 fully enrolled.
- OP-1250 + palbociclib combo: dose escalation completed, Phase 2 expansion ongoing; no dose-limiting toxicities.
- Phase 3 monotherapy study planned for mid-2023; FDA Fast Track granted for ER+/HER2- metastatic breast cancer.