earnings
confidence high
sentiment neutral
materiality 0.65
Passage Bio reports FY2022 net loss of $136.1M; cash runway into H1 2025; clinical updates for GM1 and FTD
Passage BIO, Inc.
- Cash and marketable securities $189.6M at Dec 31, 2022, down from $315.8M; runway into first half of 2025.
- FY2022 net loss $136.1M ($2.50 per share) vs $185.4M ($3.48) in 2021; R&D expenses $86.1M.
- PBGM01 for GM1 gangliosidosis: interim data shows biological effect; plan to dose first patient at higher dose in H2 2023.
- upliFT-D trial for FTD-GRN: enrollment ongoing; initial safety/biomarker data from Cohort 1 expected H2 2023.