---
schema_version: "secwatch.filing_event.v1"
accession: "0001558370-23-003169"
form_type: "8-K"
ticker: "PMN"
cik: "0001374339"
company_name: "ProMIS Neurosciences Inc."
filed_at: "2023-03-08T23:59:59+00:00"
generated_at: "2026-06-18T08:16:44.806595+00:00"
event_type: "earnings"
sentiment: "neutral"
materiality_score: 0.6
calibrated_materiality_score: 0.6
confidence: "high"
source: SEC EDGAR
---

# ProMIS Neurosciences reports 2022 net loss $18.1M, cash $5.9M, IND for PMN310 expected in 60 days

## Summary
- Net loss $18.1M in 2022 vs $9.8M in 2021; cash $5.9M vs $16.9M.
- R&D expenses rose to $16.1M from $4.6M, driven by PMN310 IND preparation.
- IND for Alzheimer's candidate PMN310 expected within 60 days; Phase 1a planned.
- Completed GLP toxicology for PMN310; no adverse effects at 5x planned highest dose.
- Discovery programs: PMN267 (ALS) and PMN442 (MSA) selected and humanized.

## SEC filing metadata
- accession: 0001558370-23-003169
- form_type: 8-K
- ticker: PMN
- cik: 0001374339
- company_name: ProMIS Neurosciences Inc.
- filed_at: 2023-03-08T23:59:59+00:00
- event_type: earnings
- sentiment: neutral
- materiality_score: 0.6
- calibrated_materiality_score: 0.6
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1374339/000155837023003169/0001558370-23-003169-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1374339/000155837023003169/pmn-20230308x8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001558370-23-003169
- JSON: https://secwatch.observer/filing/0001558370-23-003169.json
- Plain text: https://secwatch.observer/filing/0001558370-23-003169.txt

## Key facts
- Earnings Releases
  ProMIS Neurosciences Inc. reported the year ended December 31, 2022 results: net income Net loss was $18.1 million for the year ended December 31, 2022, compared to $9.8 million for the same period in 2021..
  - Period: the year ended December 31, 2022
  - Net income: Net loss was $18.1 million for the year ended December 31, 2022, compared to $9.8 million for the same period in 2021.
  - Result: reported results
  source text: reporting its financial condition and financial results as of and for the year ended December 31, 2022.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1374339/000155837023003169/0001558370-23-003169-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.