secwatch.observer — SEC 8-K summary ====================================== Issuer: ProMIS Neurosciences Inc. (PMN) CIK: 0001374339 Form: 8-K Filed at: 2023-03-08T23:59:59+00:00 Accession: 0001558370-23-003169 Event type: earnings Sentiment: neutral Materiality: 0.60 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 ProMIS Neurosciences reports 2022 net loss $18.1M, cash $5.9M, IND for PMN310 expected in 60 days -------------------------------------------------------------------------------- - Net loss $18.1M in 2022 vs $9.8M in 2021; cash $5.9M vs $16.9M. - R&D expenses rose to $16.1M from $4.6M, driven by PMN310 IND preparation. - IND for Alzheimer's candidate PMN310 expected within 60 days; Phase 1a planned. - Completed GLP toxicology for PMN310; no adverse effects at 5x planned highest dose. - Discovery programs: PMN267 (ALS) and PMN442 (MSA) selected and humanized. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1374339/000155837023003169/0001558370-23-003169-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1374339/000155837023003169/pmn-20230308x8k.htm HTML page: https://secwatch.observer/filing/0001558370-23-003169 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer