{"schema_version":"secwatch.filing_event.v1","accession":"0001558370-23-003644","form_type":"8-K","ticker":"MGTX","cik":"0001735438","company_name":"MeiraGTx Holdings plc","filed_at":"2023-03-14T23:59:59+00:00","discovered_at":"2026-05-14T18:03:46.353412+00:00","generated_at":"2026-06-18T03:31:34.667926+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"negative","materiality_score":0.65,"calibrated_materiality_score":0.65,"confidence":"high","headline":"MeiraGTx reports 2022 net loss $129.6M; pipeline advances toward 2024 BLA","bullets":["Net loss of $129.6M ($2.87/share) vs $79.6M in 2021; revenue $15.9M (down from $37.7M on lower milestone payments).","Cash and equivalents $115.5M plus $21M Janssen receivables; expected runway into Q4 2024.","Phase 3 Lumeos trial for botaretigene sparoparvovec (XLRP) enrolling; BLA submission on track for 2024.","AAV-hAQP1 for xerostomia showed 75% symptom improvement; Phase 2 planned Q2 2023.","AAV-GAD for Parkinson's dosing patients; enrollment completion anticipated Q3 2023."],"urls":{"canonical":"https://secwatch.observer/filing/0001558370-23-003644","json":"https://secwatch.observer/filing/0001558370-23-003644.json","markdown":"https://secwatch.observer/filing/0001558370-23-003644.md","text":"https://secwatch.observer/filing/0001558370-23-003644.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1735438/000155837023003644/0001558370-23-003644-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1735438/000155837023003644/mgtx-20230314x8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-18T03:31:34.667926+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[{"claim_id":"62a4702f6d4d4d1a4ee2c8295957a855bd4c79ee","claim":"MeiraGTx Holdings plc reported financial results for the year ended December 31, 2022.","evidence_excerpt":"On March 14, 2023, MeiraGTx Holdings plc (the “Company”) issued a press release announcing its financial results for the year ended December 31, 2022.","evidence_source":"SEC 8-K Item 2.02","evidence_url":"https://www.sec.gov/Archives/edgar/data/1735438/000155837023003644/0001558370-23-003644-index.htm","confidence":0.95,"family_label":"Earnings Releases","details":[{"label":"Period","value":"the year ended December 31, 2022"},{"label":"Result","value":"reported results"}],"fact_type":"earnings_release"}],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}