other material
confidence high
sentiment positive
materiality 0.70
Xilio Therapeutics announces Roche collaboration for XTX101 in MSS CRC; cash $75.4M
Xilio Therapeutics, Inc.
- Entered clinical trial collaboration with Roche; Xilio retains rights to XTX101; eligible for cost-sharing payments.
- Updated XTX101 data: durable partial response 36 wks in NSCLC; no Grade 4/5 AEs at RP2D; no colitis.
- XTX202 cleared 2.8 mg/kg dose, no vascular leak; expects preliminary Phase 1/2 data early Nov 2023 in ≥20 evaluable pts.
- Q2 net loss $19.4M vs $24.6M YoY; cash $75.4M, runway into Q2 2024.
- Promoted Chris Frankenfield to COO; XTX301 safety data expected Q4 2023.