---
schema_version: "secwatch.filing_event.v1"
accession: "0001558370-23-016284"
form_type: "8-K"
ticker: "AYTU"
cik: "0001385818"
company_name: "AYTU BIOPHARMA, INC"
filed_at: "2023-10-06T23:59:59+00:00"
generated_at: "2026-06-10T03:17:58.374364+00:00"
event_type: "leadership"
sentiment: "negative"
materiality_score: 0.8
calibrated_materiality_score: 0.8
confidence: "high"
source: SEC EDGAR
---

# Aytu BioPharma COO resigns; company winding down manufacturing, suspending R&D

## Summary
- COO Christopher Brooke resigned effective Oct 13, 2023, to join a development-stage biotech.
- Company will not replace COO due to wind down of manufacturing at Grand Prairie, TX facility.
- All pipeline research and development programs are indefinitely suspended.
- Resignation not due to any disagreement with company or auditors.

## SEC filing metadata
- accession: 0001558370-23-016284
- form_type: 8-K
- ticker: AYTU
- cik: 0001385818
- company_name: AYTU BIOPHARMA, INC
- filed_at: 2023-10-06T23:59:59+00:00
- event_type: leadership
- sentiment: negative
- materiality_score: 0.8
- calibrated_materiality_score: 0.8
- confidence: high
- sec_items: 5.02
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1385818/000155837023016284/0001558370-23-016284-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1385818/000155837023016284/aytu-20231003x8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001558370-23-016284
- JSON: https://secwatch.observer/filing/0001558370-23-016284.json
- Plain text: https://secwatch.observer/filing/0001558370-23-016284.txt

## Key facts
- Executive change
  Christopher Brooke resigned as Chief Operating Officer at AYTU BIOPHARMA, INC.
  - Action: resigned
  - Role: Chief Operating Officer
  source text: On October 3, 2023, Christopher Brooke resigned as Chief Operating Officer of Aytu BioPharma, Inc. (the “Company”), effective October 13, 2023, to pursue another opportunity at a development-stage biotechnology company.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1385818/000155837023016284/0001558370-23-016284-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.