other material
confidence high
sentiment positive
materiality 0.75
Mustang Bio: MB-106 achieves 100% complete response in follicular lymphoma in Phase 1/2
MUSTANG BIO, INC.
- 100% complete response rate in 5 follicular lymphoma patients; 100% overall response in follicular and Waldenstrom macroglobulinemia.
- Favorable safety: no CRS > Grade 1, no ICANS; outpatient administration feasible.
- Complete responses seen in patients previously treated with CD19-targeted CAR-T therapy.
- Plan to finalize Phase 2 dose in early 2024; End-of-Phase 1 FDA meeting expected H1 2024.
- Registrational trial planned for relapsed/refractory WM with 58 patients; top-line data expected mid-2026.