secwatch.observer — SEC 8-K summary ====================================== Issuer: NextCure, Inc. (NXTC) CIK: 0001661059 Form: 8-K Filed at: 2024-03-21T23:59:59+00:00 Accession: 0001558370-24-003671 Event type: earnings Sentiment: negative Materiality: 0.65 Item codes: 2.02, 7.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 NextCure reports FY2023 net loss $62.7M; workforce cut 37% to extend cash runway to H2 2026 -------------------------------------------------------------------------------- - Cash, equivalents, and marketable securities $108.3M at Dec 31, 2023 (down from $159.9M); net loss $62.7M vs $74.7M prior year. - Workforce reduction ~37%; internal GMP manufacturing paused; one-time restructuring charges ~$0.8M expected in Q2 2024. - NC410 combo: 42.8% ORR (3 PRs in 7 evaluable ovarian patients); CRC cohort 10.5% ORR (2/19), median PFS 8.1 months. - LNCB74 (B7-H4 ADC) IND planned by year-end 2024; cost-sharing with LegoChem Biosciences. - Cash runway now expected into second half of 2026 following restructuring and cost reductions. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1661059/000155837024003671/0001558370-24-003671-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1661059/000155837024003671/nxtc-20240321x8k.htm HTML page: https://secwatch.observer/filing/0001558370-24-003671 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer