other material
confidence high
sentiment positive
materiality 0.75
NeuroBo reports positive Phase 1 SAD data for DA-1726 obesity drug; no serious AEs
MetaVia Inc.
- 45 obese participants randomized 6:3 DA-1726 vs placebo; drug safe and well tolerated.
- 5 AEs in DA-1726 group vs 3 placebo; no serious adverse events reported.
- Dose-linear PK observed across investigated range; additional cohorts added to find max tolerated dose.
- MAD Part 2 top-line data expected Q1 2025; Part 3 will evaluate early proof of concept.
- CEO cites potential best-in-class profile due to balanced GLP1R and glucagon receptor activation.