other material
confidence high
sentiment neutral
materiality 0.60
NeuroBo completes Phase 2a MASH trial dosing; topline data due December 2024
MetaVia Inc.
- Last patient last visit in two-part Phase 2a trial of DA-1241, a GPR119 agonist for MASH.
- 95 of 109 randomized patients completed dosing across Part 1 (DA-1241 vs placebo) and Part 2 (DA-1241 + sitagliptin vs placebo).
- Primary endpoint: change from baseline in ALT at Week 16; secondary endpoints include lipid and safety measures.
- Topline data from both parts expected in December 2024; prior Phase 1 showed DA-1241 well tolerated.