secwatch.observer — SEC 8-K summary ====================================== Issuer: Generation Bio Co. (—) CIK: 0001733294 Form: 8-K Filed at: 2025-01-06T23:59:59+00:00 Accession: 0001558370-25-000035 Event type: other_material Sentiment: neutral Materiality: 0.75 Item codes: 5.02, 7.01, 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Generation Bio pivots to ctLNP siRNA for autoimmune diseases; CFO, CSO exit; cuts 20% staff -------------------------------------------------------------------------------- - New focus on ctLNP-delivered siRNA for T cell-driven autoimmune diseases; first IND expected 2H 2026. - CFO Matthew Norkunas departs Jan 10; Kevin Conway appointed CFO with $420K salary and 290,960 option grant. - CSO Matthew Stanton departs; Phillip Samayoa appointed CSO with $510K salary; Stanton to consult through mid-2025. - Workforce reduced ~20%; severance costs estimated $1-2M; cash runway into 2H 2027. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1733294/000155837025000035/0001558370-25-000035-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1733294/000155837025000035/gbio-20250106x8k.htm HTML page: https://secwatch.observer/filing/0001558370-25-000035 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer