---
schema_version: "secwatch.filing_event.v1"
accession: "0001559053-24-000012"
form_type: "8-K"
ticker: "PRTA"
cik: "0001559053"
company_name: "PROTHENA CORP PUBLIC LTD CO"
filed_at: "2024-05-08T23:59:59+00:00"
generated_at: "2026-06-02T09:55:05.645687+00:00"
event_type: "earnings"
sentiment: "negative"
materiality_score: 0.55
calibrated_materiality_score: 0.55
confidence: "high"
source: SEC EDGAR
---

# Prothena Q1 net loss $72.2M ($1.34/sh); cash $548.7M; guides FY 2024 cash burn $208-225M

## Summary
- Net loss $72.2M vs $46.9M YoY; revenue $0.1M vs $2.2M; R&D expenses $64.1M vs $44.8M.
- Cash, equivalents & restricted cash $548.7M (no debt); expects ~$405M year-end 2024.
- Phase 3 AFFIRM-AL (birtamimab) topline data expected 4Q24–2Q25; Phase 1 PRX012 update in 2024.
- Bristol Myers Squibb initiated Phase 2 for BMS-986446 (tau antibody) in early Alzheimer’s.
- Daniel G. Welch appointed independent director and Chair Designate; David Ford named Chief People Officer.

## SEC filing metadata
- accession: 0001559053-24-000012
- form_type: 8-K
- ticker: PRTA
- cik: 0001559053
- company_name: PROTHENA CORP PUBLIC LTD CO
- filed_at: 2024-05-08T23:59:59+00:00
- event_type: earnings
- sentiment: negative
- materiality_score: 0.55
- calibrated_materiality_score: 0.55
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1559053/000155905324000012/0001559053-24-000012-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1559053/000155905324000012/prta-20240508.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001559053-24-000012
- JSON: https://secwatch.observer/filing/0001559053-24-000012.json
- Plain text: https://secwatch.observer/filing/0001559053-24-000012.txt

## Key facts
- Earnings Releases
  PROTHENA CORP PUBLIC LTD CO reported financial results for first quarter ended March 31, 2024.
  - Period: first quarter ended March 31, 2024
  - Result: reported results
  source text: On May 8, 2024, Prothena Corporation plc issued a press release announcing its financial results for the first quarter ended March 31, 2024.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1559053/000155905324000012/0001559053-24-000012-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.