secwatch.observer — SEC 8-K summary ====================================== Issuer: PROTHENA CORP PUBLIC LTD CO (PRTA) CIK: 0001559053 Form: 8-K Filed at: 2026-02-19T23:59:59+00:00 Accession: 0001559053-26-000003 Event type: earnings Sentiment: negative Materiality: 0.75 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Prothena posts Q4 2025 net loss $21.6M; full-year loss $244.1M; 2026 cash burn guide $50-55M -------------------------------------------------------------------------------- - Net loss $21.6M ($0.40 EPS) in Q4 vs $58.0M loss ($1.08 EPS) in Q4 2024; full-year loss $244.1M ($4.53 EPS). - Total revenue $21K in Q4 vs $2.1M a year ago; full-year revenue $9.7M vs $135.2M in 2024. - Cash & restricted cash $308.4M at Dec 31, 2025; no debt; shares outstanding ~53.8M. - 2026 guidance: net cash used in ops $50-55M; year-end cash ~$255M; excludes up to $105M milestones. - Partners Roche, Novo Nordisk, BMS initiated Phase 3 trials for prasinezumab, coramitug, and BMS-986446. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1559053/000155905326000003/0001559053-26-000003-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1559053/000155905326000003/prta-20260219.htm HTML page: https://secwatch.observer/filing/0001559053-26-000003 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer