other material
confidence high
sentiment neutral
materiality 0.55
Nkarta doses first patients in NKX019 Ph1; NKX101 initial data guided to 1H 2022
Nkarta, Inc.
- First patients dosed in Phase 1 trial of NKX019 for CD19+ B-cell malignancies (NHL, CLL, B-ALL).
- Initial data from NKX019 trial expected in 2022.
- Initial data from NKX101 Phase 1 in AML/MDS now expected in first half of 2022 (previously anticipated earlier).
- NKX101 cadence affected by haplomatched donor cell use, staggered enrollment, and COVID-19 disruptions.
- Protocol amended to allow off-the-shelf or haplomatched cells and to shorten patient stagger.