secwatch.observer — SEC 8-K summary ====================================== Issuer: Prelude Therapeutics Inc (PRLD) CIK: 0001678660 Form: 8-K Filed at: 2021-11-12T23:59:59+00:00 Accession: 0001564590-21-056478 Event type: other_material Sentiment: negative Materiality: 0.75 Item codes: 2.02, 5.02, 7.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Prelude Therapeutics Q3 loss widens to $30.7M; CFO and CMO depart; cash $320.9M ------------------------------------------------------------------------------- - Q3 net loss $30.7M ($0.66/sh) vs $16.8M loss in Q3 2020; cash, equivalents and securities $320.9M. - CFO Brian Piper resigns effective Nov 19; Laurent Chardonnet appointed CFO from Nov 29. - CMO Dr. David Mauro mutually agreed to depart Nov 9; search for successor ongoing. - PRT2527 IND cleared; Phase 1 trial to start by year-end; PRT543/811 expansion data expected in 2022. - Retention bonus of $200k approved for EVP Deborah Morosini if employed through Nov 30, 2022. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1678660/000156459021056478/0001564590-21-056478-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1678660/000156459021056478/prld-8k_20211105.htm HTML page: https://secwatch.observer/filing/0001564590-21-056478 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer