{"schema_version":"secwatch.filing_event.v1","accession":"0001564590-21-057143","form_type":"8-K","ticker":"SYRE","cik":"0001636282","company_name":"Spyre Therapeutics, Inc.","filed_at":"2021-11-16T23:59:59+00:00","discovered_at":"2026-05-14T18:04:13.421843+00:00","generated_at":"2026-06-28T07:48:31.885181+00:00","sec_items":["5.02"],"event_type":"leadership","sentiment":"neutral","materiality_score":0.3,"calibrated_materiality_score":0.3,"confidence":"high","headline":"Aeglea Biotherapeutics appoints Hunter Smith to board of directors and audit committee","bullets":["Hunter Smith appointed as Class I director and Audit Committee member effective November 12, 2021.","Smith is CFO of Rhythm Pharmaceuticals (since July 2017) and previously VP Finance at Celgene.","Receives pro rata director retainer ($40,000 annual) and audit committee retainer ($7,500 annual).","Granted option to purchase 60,000 shares at closing price on November 12, 2021, vesting monthly over three years."],"urls":{"canonical":"https://secwatch.observer/filing/0001564590-21-057143","json":"https://secwatch.observer/filing/0001564590-21-057143.json","markdown":"https://secwatch.observer/filing/0001564590-21-057143.md","text":"https://secwatch.observer/filing/0001564590-21-057143.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1636282/000156459021057143/0001564590-21-057143-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1636282/000156459021057143/agle-8k_20211112.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-28T07:48:31.885181+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[{"claim_id":"197c2de01c","claim":"Hunter Smith was appointed as Class I Director at Spyre Therapeutics, Inc..","evidence_excerpt":"On November 12, 2021, the board of directors (the “Board”) of Aeglea Biotherapeutics, Inc. (the “Company”) appointed Hunter Smith as a Class I director and as a member of the Audit Committee, effective immediately.","evidence_source":"SEC 8-K Item 5.02","evidence_url":"https://www.sec.gov/Archives/edgar/data/1636282/000156459021057143/0001564590-21-057143-index.htm","confidence":1.0,"family_label":"Executive change","details":[{"label":"Action","value":"appointed"},{"label":"Role","value":"Class I Director"}],"fact_type":"executive_change"}],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}