---
schema_version: "secwatch.filing_event.v1"
accession: "0001564590-22-006692"
form_type: "8-K"
ticker: "SDGR"
cik: "0001490978"
company_name: "Schrodinger, Inc."
filed_at: "2022-02-24T23:59:59+00:00"
generated_at: "2026-06-27T04:45:14.912260+00:00"
event_type: "earnings"
sentiment: "neutral"
materiality_score: 0.75
calibrated_materiality_score: 0.75
confidence: "high"
source: SEC EDGAR
---

# Schrödinger Q4 software revenue $38.6M, up 55% YoY; guides 2022 total revenue $161-181M

## Summary
- Q4 total revenue $46.2M (+40% YoY); software revenue $38.6M (+55% YoY); drug discovery $7.6M.
- FY 2021 total revenue $137.9M (+28% YoY); net loss $101.2M vs $26.6M loss in 2020.
- 2022 guidance: total revenue $161-181M; software $126-136M; drug discovery $35-45M; gross margin mid-70s%.
- Karen Akinsanya promoted to president of R&D; MALT1 IND H1 2022; Phase 1 study in H2 2022.
- Cash $579M; ACV $112.1M (+22% YoY); 190 customers >$100k ACV.

## SEC filing metadata
- accession: 0001564590-22-006692
- form_type: 8-K
- ticker: SDGR
- cik: 0001490978
- company_name: Schrodinger, Inc.
- filed_at: 2022-02-24T23:59:59+00:00
- event_type: earnings
- sentiment: neutral
- materiality_score: 0.75
- calibrated_materiality_score: 0.75
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1490978/000156459022006692/0001564590-22-006692-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1490978/000156459022006692/sdgr-8k_20220224.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001564590-22-006692
- JSON: https://secwatch.observer/filing/0001564590-22-006692.json
- Plain text: https://secwatch.observer/filing/0001564590-22-006692.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.