{"schema_version":"secwatch.filing_event.v1","accession":"0001564590-22-017853","form_type":"8-K","ticker":"RGNX","cik":"0001590877","company_name":"REGENXBIO Inc.","filed_at":"2022-05-04T23:59:59+00:00","discovered_at":"2026-05-14T18:04:01.347388+00:00","generated_at":"2026-06-26T00:43:00.195946+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"negative","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"REGENXBIO Q1 net loss widens to $76.7M; delays RGX-202 Duchenne trial initiation to H1 2023","bullets":["Net loss of $76.7M ($1.79/sh) vs $50.1M loss ($1.20/sh) in Q1 2021; revenue $22.2M up 17% YoY on Zolgensma royalties.","Cash $764.8M, operational runway into 2025; net loss includes $9.2M non-recurring charge from UPenn license amendment.","RGX-314 pivotal trials for wet AMD on track; BLA submission expected in 2024.","RGX-202 Duchenne trial dosing delayed to H1 2023 due to manufacturing observation; trial prep continues.","cGMP manufacturing facility operational for up to 2000L scale; '5x'25' strategy to advance five AAV therapeutics by 2025."],"urls":{"canonical":"https://secwatch.observer/filing/0001564590-22-017853","json":"https://secwatch.observer/filing/0001564590-22-017853.json","markdown":"https://secwatch.observer/filing/0001564590-22-017853.md","text":"https://secwatch.observer/filing/0001564590-22-017853.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1590877/000156459022017853/0001564590-22-017853-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1590877/000156459022017853/rgnx-8k_20220504.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-26T00:43:00.195946+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}