secwatch.observer — SEC 8-K summary ====================================== Issuer: LENZ Therapeutics, Inc. (LENZ) CIK: 0001815776 Form: 8-K Filed at: 2022-05-12T23:59:59+00:00 Accession: 0001564590-22-019849 Event type: earnings Sentiment: positive Materiality: 0.65 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Graphite Bio Q1 net loss $25.8M; on track to dose first SCD patient in H2 2022 ------------------------------------------------------------------------------ - Net loss $25.8M ($0.48 per share); R&D spend $18.2M, G&A $7.7M. - Cash, equivalents and investments $352.1M as of March 31, 2022; runway into Q4 2024. - GPH101 for sickle cell disease received FDA Fast Track Designation; first patient dosing target H2 2022, proof-of-concept data in 2023. - GPH102 for beta-thalassemia preclinical data presented at ASGCT; IND submission expected by mid-2024. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1815776/000156459022019849/0001564590-22-019849-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1815776/000156459022019849/grph-8k_20220512.htm HTML page: https://secwatch.observer/filing/0001564590-22-019849 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer