other_material
confidence medium
sentiment negative
materiality 0.60
Intensity Therapeutics pauses INVINCIBLE-4 enrollment after skin irritation; first Cohort A patient achieves pCR
INTENSITY THERAPEUTICS, INC.
- First patient in Cohort A achieved pathological complete response after two INT230-6 doses plus immunochemotherapy.
- Cohort A patients received INT230-6 eight days apart followed by standard-of-care immunochemotherapy.
- Safety profile described as favorable, but localized skin irritation near tumor site observed in some patients.
- Enrollment paused to evaluate data and implement adjustments before reopening.
item 8.01